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#473631
Chrissy Durrough
Keymaster

Hi Adam,

Thanks for this question! The nigrostriatal pathway is active whenever the direct and indirect pathways are active. It is only added later in the slides for clarity and to demonstrate the effect of Parkinson’s disease on the direct and indirect pathways because the substantia nigra (and, therefore, dopamine) are introduced in the nigrostriatal pathway.

Hope this helps!

Chrissy