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OVER 98% PASS RATE FOR THE NCS, OCS, AND PCS EXAMS › forums › NCS Advantage › Direct vs Indirect Pathway: › Reply To: Direct vs Indirect Pathway:

March 9, 2021 at 9:10 am #473631
Chrissy Durrough Lugge
Keymaster

Hi Adam,

Thanks for this question! The nigrostriatal pathway is active whenever the direct and indirect pathways are active. It is only added later in the slides for clarity and to demonstrate the effect of Parkinson’s disease on the direct and indirect pathways because the substantia nigra (and, therefore, dopamine) are introduced in the nigrostriatal pathway.

Hope this helps!

Chrissy