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    • #490850
      Leah Sawyer
      Participant

      COPD decreases ventilation? Is that correct? I have always read that COPD would increase respiratory rate… (Question is below, I selected D)
      45. Which of the following conditions would most likely result in a high V/Q ratio?

      a. Pulmonary embolismcorrect
      b. Increased alveolar perfusion
      c. Wearing a N95 mask 8hrs/day
      d. COPD wrong

      V/Q ratio is the ratio of ventilation (V. the amount of air that enters and leaves the alveoli) to perfusion (Q. the amount of blood that flows to the alveolar capillaries). A high V/Q ratio would mean there is increased ventilation or decreased perfusion. A PE is the only condition that would result in this. COPD and wearing a N95 mask would both decrease ventilation.
      References:
      1. Taffet, G. (2021) Normal Aging. Up to Date.

    • #490851
      Ciera Stitz
      Participant

      Hi Leah! My understanding is that you are correct in that COPD increases breathing rate, but this is compensatory due to the decreased ventilation. Similar to when a disease decreases cardiac output there is a compensatory increase in HR. It is the body’s way of compensating for the natural decline in ventilation.

    • #490861
      Jonathan Zins
      Participant

      Good question Leah, Ciera’s explanation is spot on. COPD typically causes low V/Q ratio due to airway obstruction and poor ventilation relative to perfusion. (Some emphysematous regions may have high V/Q, but overall COPD is categorized as a low V/Q condition.)

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